Vitiligo

Vitiligo is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. As a result, white patches appear on the skin in different parts of the body. Similar patches also appear on both the mucous membranes (tissues that line the inside of the mouth and nose) and the retina (inner layer of the eyeball). The hair that grows on areas affected by vitiligo sometimes turns white.
The cause of vitiligo is not known, but doctors and researchers have several different theories. There is strong evidence that people with vitiligo inherit a group of three genes that make them susceptible to depigmentation. The most widely accepted view is that the depigmentation occurs because vitiligo is an autoimmune disease -- a disease in which a person's immune system reacts against the body's own organs or tissues. People's bodies produce proteins called cytokines that, in vitiligo, alter their pigment-producing cells and cause these cells to die. Another theory is that melanocytes destroy themselves. Finally, some people have reported that a single event such as sunburn or emotional distress triggered vitiligo; however, these events have not been scientifically proven as causes of vitiligo.
Suction Blister
Suction blister epidermal grafting is an established technique for the treatment of resistant and stable vitiligo especially over small and cosmetically important areas like the face. However, certain areas, such as lips and eyelids, require special considerations because of their anatomic peculiarities.

Phototherapy
Phototherapy (treatment with light) may be used for children or adults if:

  • other treatments have not worked
  • the vitiligo is widespread
  • the vitiligo is having a significant impact on their quality of life
Evidence suggests that phototherapy, particularly when combined with other treatments, has a positive effect on vitiligo. During phototherapy, your skin is exposed to ultraviolet A (UVA) or ultraviolet B (UVB) light from a special lamp.
This type of treatment is sometimes called PUVA (psoralen and ultraviolet A light).

Skin grafts
A skin graft is a surgical procedure that involves removing healthy skin from an unaffected area of the body and using it to cover an area where the skin has been damaged or lost. To treat vitiligo, a skin graft can be used to cover the white patch.
Skin grafts may be considered for adults in areas that are affecting your appearance if:
  • no new white patches have appeared in the last 12 months
  • the white patches have not gotten worse in the last 12 months
  • your vitiligo was not triggered by damage to your skin, such as severe sunburn (known as the Koebner response)
Non Culture Melanger Transfer